News Takeoff41 launches feasibility study at Stanford NICU →

The intelligent TPN ordering system for NICUs.

Leverage advanced AI to improve perinatal care. TPN2.0 turns nutritional goals into safe, compoundable orders seamlessly within your existing EHR.

Epic Integration / TPN2.0 Instance

AI-Guided Formulation Recommendation
Patient Chemistry & Target Fluid Goal Evaluated. 15 Parameters optimized.
Total Fluid
140 mL/kg/d
Osmolarity (Safe)
850 mOsm/L
Confirm Order

Validated by science. Trusted by institutions.

Stanford University Nature Medicine Science Translational Medicine NIH FDA Reviewed

Clinical complexity turned into precision care.

Use a foundation of validated AI alongside automated fluid tracking to ensure precision and safety for every patient.

Native EHR Integration

Launch and operate TPN2.0 directly within your EHR. Complete fluid visibility is achieved by capturing every drip, line, and feed order in one place before ordering your TPN. Orders flow back seamlessly.

EHR Instance
Patient Info, Lines, Feeds
TPN2.0 AI
Fluid Balancing & Calc
TPN Order
Safe, Compoundable

AI-Guided Formulations

Get a head start on every order with personalized recommendations validated on 100,000+ neonatal TPN prescriptions. No black boxes—understand the 'why' behind every number.

Intrinsic Safety Guardrails

Every recommendation is governed by pharmacological constraints. Automatically evaluate osmolarity, precipitation, and other cutoffs to reduce the burden on the provider team.

Unified Caloric Intelligence

Eliminate the manual reconciliation of enteral and intravenous intake. Aggregate calories from all TPN, enteral, and IV sources into a single view to visualize macro and micro-nutrient contribution trends.

Enteral40%
TPN Intravenous60%

Evidence-based AI, validated by peer review.

Our core philosophy is to develop clinical tools fundamentally rooted in validated science.

Science & Research

AI-guided precision parenteral nutrition for NICUs

Training an AI model on a decade of TPN prescriptions from over 9,000 patients. TPN2.0 identified 15 standardized formulas that matched expert-level quality, rating higher than current best practice in blinded tests.

FDA Update

TPN2.0 completes FDA review

The FDA determined TPN2.0 does not meet the definition of a regulated medical device because clinicians always review, adjust, or override recommendations. Cleared for hospital deployment.

Clinical Study

Feasibility study at Stanford NICU

Takeoff41 initiated a clinical feasibility study enrolling 260 infants, marking the first time TPN2.0 has been deployed in a live clinical environment integrated into Epic.

Empower your clinical judgment today.

Backed by enterprise-grade security, SOC 2 Type II compliance, and rigorous HIPAA safeguards. Adaptable to your institution's specific clinical governance.

SOC 2 Type II
HIPAA Compliant
Schedule a Demo